Eugene plays the role of Dr. Lola Cardenas, an alluring psychiatrist/sex therapist popularly known as "Hot Mama." She hosts a late night radio program kung saan nagbibigay siya ng advice to callers who ask questions, about love and intimacy. Lola displays a very liberal and open-minded personality as Hot Mama but unknown to many, isa pala siyang old maid who leads a simple and carefree life. Despite being an expert sex therapist, malamig ang sex life ni Lola and worse, she hasn't found her Mr. Right yet. Single, lonely and desperate for love, she soon finds herself obsessed with Bruce (Victor Aliwalas), ang kanyang executive producer/friend. Pero, in love na ito sa kanyang cousin/manager Mari (Maureen Larrazabal). Devastated for being loveless, Hot Mama focuses her attention on her career at sa isang social networking website. Here she meets Randy (Wendell Ramos), one of her avid fans from Cebu. Lola is intrigued with Randy and after a while, a special friendship develops between them. At nang gusto nang makipagkita ni Randy kay Lola bakit kaya ayaw ni Lola? Hindi kasi confident si Hot Mama na tatanggapin si ng mga tao for who she really is--simpleng si Dra. Lola. What will Hot Mama do if Randy shows up to meet her? Will Randy accept the person behind Hot Mama? Will they be the perfect sweethearts? SRO Cinemaserye presents Hot Mamas airs Thursday nights starting March 11, right after Queen Seon Deok sa GMA Telebabad.