'The Secrets of Hotel 88' tells the story of three estranged brothers who discovered that they are part of the same family. And while they will inherit a hotel, they will also inherit its secrets.

However, a rival family claims their rights on the land where the hotel stands, and a fight to take the hotel ensues, and the secrets that are kept starts to get uncovered.

'The Secrets of Hotel 88' is the first project of the former 'Pinoy Big Brother Celebrity Collab Edition' housemates, namely Mika Salamanca and Brent Manalo, AZ Martinez, Ralph De Leon, River Joseph, Klarisse De Guzman, Esnyr, Xyriel Manabat, Josh Ford, Kira Balinger, Dustin Yu, Bianca De Vera, and Will Ashley. They will also be joined by veteran actors like Ina Raymundo, Gardo Versoza, and Dominic Ochoa.