Neil Ryan Sese is a seasoned actor who has been thriving in the industry with his charisma and versatile acting skills. In GMA, he became part of a number of well-received Kapuso shows such as "Encantadia," "Bihag," "Babawiin Ko Ang Lahat" and the Filipino adaptation of hit K-drama series "Descendants of the Sun." He is set to appear in the much-awaited live action adaptation "Voltes V: Legacy" where he will play the role of Dr. Hook. Neil Ryan is also a favorite of film directors and starred in several mainstream and indie titles over the course of his career.
| 2023 | Voltes V: Legacy | Dr. Hook |
| 2023 | Magpakailanman: My Third Life: The Kim Atienza Story | Lito Atienza |
| 2023 | Magpakailanman: Inang Walang Pamilya | Bernard |
| 2022 | Start-Up PH | Chito Sison |
| 2022 | Magpakailanman: Ang Bulag na Ilaw ng Tahanan: The Jane and Jes Orlino Story | Jes |
| 2022 | Magpakailanman: My Father's Killer | Mario |
| 2022 | Daig Kayo ng Lola Ko: Tammy Tamad | Edward |
| 2021 | Tadhana: In the Name of Love | Larry |
| 2021 | Babawiin Ko Ang Lahat | Inspector Jun / Inspector Jun Cruz |
| 2021 | Magpakailanman: Masahistsa For Hire | Raul |
| 2021 | Magpakailanman: Masahista for Hire | Raul |
| 2021 | Dear Uge: The Bwisitor | Mon |
| 2020 | Descendants of the Sun | Rodel Dela Cruz |
| 2020 | Dear Uge: My Forgettable Love | Migs |
| 2019 | Dear Uge: Ateng Kupitera vs. Jowang Huthutera | Amante |
| 2019 | Magpakailanman: Mamili ka, Ako o Anak ko? | Manuel |
| 2019 | Dear Uge: Kalma, Mader | Rolly |
| 2019 | Tadhana: Chop Chop | Tom |
| 2019 | Tadhana: Akin ang Anak Ko | Jamal |
| 2019 | Magpakailanman: My Unlawful Husband | Ryan |
| 2019 | Bihag | Amado Anzures |
| 2018 | Onanay | Emman Cruz |
| 2018 | Ika-5 Utos | Randy Lorenzo |
| 2018 | Contessa | Eric |
| 2018 | Ang Forever Ko'y Ikaw | Lance Dimaigue |
| 2018 | Magpakailanman: The Haunted Wife | Johnny |
| 2018 | Magpakailanman: A Ghost from My Past: The Jade Martin Story | Ronald |
| 2018 | Dear Uge: Basta Dubber, Sweet Lover | Deo |
| 2018 | Daig Kayo ng Lola Ko: Ang Kuwento sa Likod ng Bahay Kubo | Ronald |
| 2017 | Daig Kayo ng Lola Ko: Golda and the Three Pandas | Golda's Father |
| 2017 | Tadhana: Aishiteiru: Mahal Kita | Jiro |
| 2017 | Super Ma'am | Arjay |
| 2017 | Magpakailanman: Laglag Bata: Ang Ina kong Abortionista | Joel |
| 2016 | Dear Uge: Faking Girls | Anthony |
| 2016 | Magpakailanman: BFF kong Duwende | Lester |
| 2016 | Encantadia | Asval |
| 2016 | Wish I May | Gabo Villafuerte |
| 2015 | Beautiful Strangers | Joaquin Acosta |
| 2015 | Let the Love Begin | Hesse |
| 2015 | Magpakailanman: Don't Chat with Strangers | Edgar |
| 2014 | Magpakailanman: Ang Byudang Naka-itim: The Rebecca Laurente Story | Vic |
| 2014 | Magpakailanman: Nakakulong na Puso | Paul |
| 2014 | Niño | David Inosente |
| 2014 | Paraiso Ko'y Ikaw | Roberto Enriquez |
| 2013 | Magpakailanman: Kambal na Sapi | Tatay Juanito |
| 2013 | Adarna | Kestrel |
| 2013 | Anna Karenina | Abel Barretto |
| 2013 | Love and Lies | Ricardo Salvador |
| 2013 | Indio | Kardo |
| 2013 | Magpakailanman: Child Rape Video Scandal: The Jessa Aquino Story | Angelo |
| 2012 | My Daddy Dearest | Val |
| 2012 | Paroa: Ang Kuwento ni Mariposa | Armando Villamor |
| 2012 | Pahiram Ng Sandali | Andrew Gomez |
| 2011 | Munting Heredera | Simeon |