DIYARBAKIR/ANKARA, Turkey - A major earthquake of magnitude 7.8 struck central Turkey and northwest Syria on Monday, killing about 300 people and injuring hundreds as buildings collapsed across the region, triggering searches for survivors in the rubble.
The quake, which hit in the early darkness of a winter morning, was also felt in Cyprus and Lebanon.
"I have never felt anything like it in the 40 years I've lived," said Erdem, a resident of the Turkish city of Gaziantep, near the quake's epicenter, who declined to give his surname.
"We were shaken at least three times very strongly, like a baby in a crib."
Turkey's disaster agency said 76 people had been killed, and 440 hurt, as authorities scrambled rescue teams and supply aircraft to the affected area, while declaring a "level 4 alarm" that calls for international assistance.
State broadcaster RTR showed rescue workers in Osmaniye province using a blanket to carry an injured man out of a collapsed four-storey building and putting him in an ambulance. He was the fifth to be pulled from the rubble, it said.
Footage on broadcaster CNNTurk showed the historic Gaziantep Castle was severely damaged.
President Tayyip Erdogan spoke by telephone with the governors of eight affected provinces to gather information on the situation and rescue efforts, his office said in a statement.
A Syrian health official said more than 230 people had been killed and some 600 injured there, most in the provinces of Hama, Aleppo and Latakia, where numerous buildings tumbled down.
"The situation is very tragic, tens of buildings have collapsed in the city of Salqin," a member of the White Helmets rescue organization said in a video clip on Twitter, referring to a town about 5 km (3 miles) from the Turkish border.
Home were "totally destroyed", said the rescuer on the clip, which showed a street strewn with rubble.
President Bashar al-Assad was holding an emergency cabinet meeting to review the damage and discuss the next steps, his office said.
State television showed footage of rescue teams searching for survivors in heavy rain and sleet. Health officials urged the public to help take the injured to emergency rooms.
"Wounded people are still arriving in waves," Aleppo's health director, Ziad Hage Taha, told Reuters by telephone.
The Greek Orthodox Archdiocese in Aleppo posted photographs of blocks of stone that had crashed down onto its mezzanine.
In nearby countryside, rescuers carried a bloodied, wailing baby out of a collapsed building, while, in the town of Azaz, a crane prised away slabs of concrete as rescuers carried away a body wrapped in a sheet.
Many buildings in the region had already suffered damage in fighting during Syria's nearly 12-year-long civil war.
People in Damascus, and in the Lebanese cities of Beirut and Tripoli, ran into the street and took to their cars to get away from their buildings in case they collapsed, witnesses said.
The United States was "profoundly concerned" about the quake in Turkey and Syria and was monitoring events closely, White House national security adviser Jake Sullivan said on Twitter.
"I have been in touch with Turkish officials to relay that we stand ready to provide any and all needed assistance," he said.
The US Geological Survey said the magnitude 7.8 quake struck at a depth of 17.9 km. It reported a series of earthquakes, one of 6.7 magnitude.
The region straddles seismic fault lines.
Focus on search and rescue
The tremor lasted about a minute and shattered windows, according to a Reuters witness in Diyarbakir, 350 km (218 miles)to the east, where a security official said at least 17 buildings collapsed.
Authorities said 16 structures collapsed in Sanliurfa and 34 in Osmaniye.
Broadcasters TRT and Haberturk showed footage of people picking through building wreckage, moving stretchers and seeking survivors in the city of Kahramanmaras, where it was still dark.
"Our primary job is to carry out the search and rescue work and to do that all our teams are on alert," Turkish Interior Minister Suleyman Soylu told reporters.
Tremors were also felt in the Turkish capital of Ankara, 460 km (286 miles) northwest of the epicenter, and in Cyprus, where police reported no damage.
"The earthquake struck in a region that we feared. There is serious widespread damage," Kerem Kinik, the chief of the Turkish Red Crescent relief agency, told Haberturk, issuing an appeal for blood donations.
Turkey is among the most earthquake-prone countries in the world. More than 17,000 people were killed in 1999 when a 7.6-magnitude quake struck Izmit, a city southeast of Istanbul. In 2011, a quake in the eastern city of Van killed more than 500. —Reuters